Claude Opus 4.5 is available directly through Anthropic’s API and is also hosted on the major cloud providers that partner with Anthropic: Amazon Web Services, Google Cloud, and Microsoft Azure. This means enterprises can choose between calling Anthropic’s API directly or using cloud-native integrations that support private networking, identity management, and compliance frameworks. For organizations already using one of these clouds, choosing the matching integration can simplify governance and deployment.
On Microsoft Azure, Claude Opus 4.5 is integrated into Microsoft Foundry, which provides Azure-native endpoints, RBAC, and observability. Azure customers can call Claude Opus 4.5 through Foundry to keep traffic within Azure infrastructure and align with existing security policies. On AWS, Claude Opus 4.5 is available through Amazon Bedrock, allowing applications to interact with the model using Bedrock’s API alongside AWS IAM controls. On Google Cloud, Claude Opus 4.5 is accessible through Vertex AI, making it easy to plug into pipelines, Model Garden, and GKE workloads.
For most enterprise architectures, the choice of hosting location is influenced by where application data lives. If your retrieval system or embeddings are stored in a vector database such as Milvus or Zilliz Cloud running in a specific region, it often makes sense to deploy the Claude Opus 4.5 endpoint close to that data to minimize latency. In regulated industries, cloud-native integrations can also simplify audit requirements. Regardless of which provider you choose, the core capabilities of Claude Opus 4.5 remain consistent across platforms, so the decision is largely about operational fit rather than differences in functionality.