Yes. Claude Opus 4.5 can manage cross-session memory through explicit memory tools and persistent artifacts rather than relying on hidden model-side memory. Anthropic provides a memory tool that allows the model to read, write, and update files in a designated memory directory. These memory files persist between sessions because they exist in your environment, not inside the model. This gives you an auditable, controlled form of long-term state while allowing Claude to access and update it during tool-enabled sessions.
Anthropic also offers Claude Memory, an opt-in feature designed for long-term personalization in chat settings. While Claude Memory stores user-specific preferences or context over time, production agent systems typically rely on explicit memory tools instead. This keeps control in your hands: you can inspect, edit, or delete stored facts, and you avoid any ambiguity about what the model is retaining. The Claude Agent SDK uses this principle extensively, encouraging agents to write progress logs, state files, and task queues that persist across runs.
Memory becomes even more powerful when paired with retrieval. Long-lived projects often include not just small preference files but also large knowledge bases: code repositories, research documents, logs, or reports. These fit naturally inside a vector database such as Milvus or Zilliz Cloud. Your agent can call a retrieval tool to fetch relevant pieces on demand, while the memory tool stores smaller structured items like goals, summaries, or plan states. Together, this gives Claude Opus 4.5 reliable cross-session continuity with clear boundaries, making agents easier to debug, observe, and trust in production.